中科院动物研究所导师介绍:周光飚
13.Liu Z,Ma L,Zhou GB.The main anticancer bullets of the chinese medicinal herb,thunder god vine.Molecules.2011;16:5283-5297.
14.Ma L,Wen ZS,Hu Z,Liu Z,Ma J,Chen XQ,Liu YQ,Pu JX,Xiao WL,Sun
HD,Zhou GB*.Overexpression and small molecule-triggered downregulation
of CIP2A in lung cancer.PLoS One,2011;6(5):e20159.
15.Liu Y,Chen XQ,Liang HX,Zhang FX,Zhang B,Jin J,Chen YL,Cheng YX,Zhou
GB.Small compound 6-O-angeloylplenolin induces mitotic arrest and
exhibits therapeutic potentials in multiple myeloma.PLoS
ONE,2011;6(7):e21930.
16.Chen SJ,Zhou GB,Zhang XW,Mao JH,The De H,Chen Z.From an old remedy
to a magic bullet:molecular mechanisms underlying the therapeutic
effects of arsenic in fighting leukemia.Blood,2011;117:6425-6437.
17.Wu W,Li Z,Zhou G,Jiang S.Total synthesis of argyrins A and E.Tetrahedron Letters,2011;52:2488-2491.
18.Xiao Q,Liu Y,Qiu Y,Zhou G,Mao C,Li Z,Yao ZJ,Jiang S.Potent
antitumor mimetics of annonaceous acetogenins embedded with an aromatic
moiety in the left hydrocarbon chain part.J Med Chem.2011;54:525-33.
19.胡政,周桂生,周光飚.肿瘤的分子靶向疗法.中国医药生物技术,2010,5:335-341.(通讯作者)
20.Zhou GS,Hu Z,Fang HT,Zhang FX,Pan XF,Chen XQ,Hu AM,Xu L,Zhou
GB.Biologic activity of triptolide in t(8;21) acute myeloid leukemia
cells.Leuk Res.2011;35:214-218.(通讯作者)
21.Zhang XW,Yan XJ,Zhou ZR,Yang FF,Wu ZY,Sun HB,Liang WX,Song
AX,Lallemand-Breitenbach V,Jeanne M,Zhang QY,Yang HY,Huang QH,Zhou
GB,Tong JH,Zhang Y,Wu JH,Hu HY,de Thé H,Chen SJ,Chen Z.Arsenic trioxide
controls the fate of the PML-RARalpha oncoprotein by directly binding
PML.Science.2010,328:240-3.
22.Zeng X,Yin BL,Hu Z,Liao CZ,Liu JL,Li S,Li Z,Nicklaus MC,Zhou
GB,Jiang S.Total Synthesis and Biological Evaluation of Largazole and
Derivatives with Promising Selectivity for Cancers Cells.Org
Lett.2010;12:1368-71.(通讯作者)
23.Chen SJ,Chen XP,Zhou GB.Healthy people,healthy journal.Frontiers of Medicine in China.2010;4:1-2.
24.Hu Z,Pan XF,Wu FQ,Ma LY,Liu DP,Liu Y,Feng TT,Meng FY,Liu XL,Jiang
QL,Chen XQ,Liu JL,Liu P,Chen Z,Chen SJ,Zhou GB.Synergy between
proteasome inhibitors and imatinib mesylate in chronic myeloid
leukemia.PLoS ONE.2009;4:e6257.(通讯作者)
25.Ding LF,Liu Y,Liang HX,Liu DP,Zhou GB and Cheng YX.Two new terpene
glucosides and antitumor agents from Centipeda minima.Journal of Asian
Natural Products Research,2009;11:732-736.(通讯作者)
26.Zeng GZ,Tan NH,Ji CJ,Fan JT,Huang HQ,Han HJ,Zhou GB.Apoptosis
inducement of bigelovin from Inula helianthus-aquatica on human Leukemia
U937 cells.Phytother Res.2009;23:885-891.(通讯作者)
27.方海同,胡政,周光飚.一种基于绿色荧光蛋白的蛋白酶体抑制剂细胞筛选模型.生物工程学报,2009;25:452-456.(通讯作者)
28.冯婷婷,普建新,胡政,刘大鹏,孙汉董,周光飚.二萜化合物Rabdocoetsin B抑制蛋白酶体功能并诱导t(8;21)白血病细胞凋亡.生物工程学报,2009;25:1218-1224
29.Zhou GB,Kang H,Wang L,Gao L,Liu P,Xie J,Zhang FX,Weng XQ,Shen
ZX,Chen J,Gu LJ,Yan M,Zhang DE,Chen SJ,Wang ZY,Chen Z.Oridonin,a
diterpenoid extracted from medicinal herbs,targets AML1-ETO fusion
protein and shows potent antitumor activity with low adverse effects on
t(8;21) leukemia in vitro and in
vivo.Blood.2007;109:3441-3450.(并列第一、通讯作者)
30.Wang L*,Zhou GB*,Liu P,* Song JH*,Liang Y*,Yan XJ,Xu F,Wang BS,Mao
JH,Shen ZX,Chen SJ,Chen Z.Dissection of mechanisms of Chinese medicinal
formula Realgar-Indigo naturalis as an effective treatment for
promyelocytic leukemia.Proc Natl Acad Sci U S
A,2008;105:4826-4831.(*:并列第一作者)
31.Wang YY*,Zhou GB*,Yin T*,Chen B,Shi JY,Liang WX,Jin XL,You JH,Yang
G,Shen ZX,Chen J,Xiong SM,Chen GQ,Xu F,Liu YW,Chen Z,Chen SJ.AML1-ETO
and C-KIT mutation/overexpression in t(8;21) leukemia:implication in
stepwise leukemogenesis and response to Gleevec.Proc Natl Acad Sci U S
A.2005;102:1104-1109.(*:并列第一作者)
32.Hu J,Liu YF,Wu QF,Xu F,Shen ZX,Zhu YM,Li JM,Tang W,Zhao WL,Wu W,Sun
HP,Chen QS,Chen B,Zhou GB,Zelent A,Waxman S,Wang ZY,Chen SJ,Chen
Z.Long-term efficacy and safety of all-trans retinoic acid/arsenic
trioxide based therapy in newly diagnosed acute promyelocytic
leukemia.Proc Natl Acad Sci U S A.2009;106:3342-3347.
33.Wang L,Zhao WL,Yan JS,Liu P,Sun HP,Zhou GB,Weng ZY,Wu WL,Weng
XQ,Sun XJ,Chen Z,Sun HD,Chen SJ.Eriocalyxin B induces apoptosis of
t(8;21) leukemia cells through NF-kappaB and MAPK signaling pathways and
triggers degradation of AML1-ETO oncoprotein in a caspase-3-dependent
manner.Cell Death Differ.2007;14:306-317.
34.Shen Y,Xu Q,Han Z,Liu H,Zhou GB.Analysis of phenotype-genotype
connection:the story of dissecting disease pathogenesis in genomic era
in China,and beyond.Philos Trans R Soc Lond B Biol
Sci.2007;362:1043-1061.(通讯作者)
35.陈竺,陈赛娟,周光飚.实验血液学架起实验室与临床的桥梁-血液学的希望.中国实验血液学杂志,2008;16:1-21.
36.周光飚,王振义.诱导分化治疗急性白血病的研究进展.中华血液学杂志,2002;23(1):49-51.
37.Chen SJ,Zhou GB,Bai XT,Chen Z.Nucleoporin.In:Schwab M,ed.Encyclopedia of Cancer:Springer Berlin Heidelberg;2008:2124-2126.
38.Zhou GB,Chen SJ,Wang ZY,Chen Z.Back to the future of
oridonin:again,compound from medicinal herb shows potent antileukemia
efficacies in vitro and in vivo.Cell Res.2007;17:274-276.
39.Zhou GB,Li G,Chen SJ,Chen Z.From dissection of disease pathogenesis
to elucidation of mechanisms of targeted therapies:leukemia research in
genomic era.Acta Pharmacol Sin.2007;28:1434-1449.
40.Zhou GB,Zhang J,Wang ZY,Chen SJ,Chen Z.Treatment of acute
promyelocytic leukaemia with all-trans retinoic acid and arsenic
trioxide:a paradigm of synergistic molecular targeting therapy.Philos
Trans R Soc Lond B Biol Sci.2007;362:959-971.
41.Chen LJ,Dong Y,Chen SY,Zhang L,Zhou GB,Chen B,Wang L,Chen Z,Chen
SJ.[hCG-PLZF-RARalpha/hCG-RARalpha-PLZF transgenic mice developing into
leukemia] Zhongguo Shi Yan Xue Ye Xue Za Zhi.2005;13:924-931.
42.董颖,陈丽娟,陈思宇,张龙,周光飚,王龙,陈赛娟.hCG/RARα/PLZF转基因小鼠发生髓系增殖性疾病.中华血液学杂志,2004;25:745-747.
43.Zhou GB,Chen SJ,Chen Z.Acute promyelocytic leukemia:a model of
molecular target based therapy.Hematology.2005;10 Suppl 1:270-280.
44.Zhou GB,Zhao WL,Wang ZY,Chen SJ,Chen Z.Retinoic acid and arsenic
for treating acute promyelocytic leukemia.PLoS Med.2005;2:e12.
45.Zhang GS,Zhou GB,Dai CW.Upregulation and activation of caspase-3 or
caspase-8 and elevation of intracellular free calcium mediated
apoptosis of indomethacin-induced K562 cells.Chin Med J
(Engl).2004;117:978-984.
46.Zhang G,Tu C,Zhang G,Zhou G,Zheng W.Indomethacin induces apoptosis
and inhibits proliferation in chronic myeloid leukemia cells.Leuk
Res.2000;24:385-392.
47.周光飚,张广森.吲哚美辛诱导K562细胞凋亡过程中半胱天冬酶及细胞内游离钙浓度的变化.中华血液学杂志,2001;21:241-244.
48.周光飚,董颖,王月英,印彤,亢卉,陈竺,陈赛娟.白血病致病基因产物靶向治疗:从急性早幼粒到其他类型白血病.中国科学(C辑).2004,34:487-500.
49.Hu J,Zhou GB,Wang ZY,Chen SJ,Chen Z.Mutant transcription factors
and tyrosine kinases as therapeutic targets for leukemias:from acute
promyelocytic leukemia to chronic myeloid leukemia and beyond.Advances
in CANCER RESEARCH.2007;98:191-220.
50.周光飚.对八纲辨证发展的思考.中国中西医结合杂志,2002;22:233-234.
51.扶云碧,孙启鑫,孟凡义,谢军,周光飚.蛋白酶体抑制剂硼替佐米诱导髓系白血病细胞株HL60凋亡的机制研究.中华医学杂志.2006;86:2413-2416.
52.周光飚.急性早幼粒细胞性白血病的诱导分化与凋亡疗法.见:陈赛娟,主编.血液恶性疾病基因异常和靶向治疗.上海科学技术出版社.2006:159-190.
53.周光飚,王月英.急性粒细胞性白血病(M2b型)多步骤发病机制及靶向治疗策略.见:陈赛娟,主编.血液恶性疾病基因异常和靶向治疗.上海科学技术出版社.2006:190-206.
54.周光飚.肿瘤具有两面性吗.医学与哲学,1999;20:19-20.
55.周光飚.弓形虫病1例.临床荟萃,1996;11:192.
56.周光飚.炸药外洗致溶血1例.中国实用内科杂志,1996;16:554.
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